Case Series A case series also known as a clinical series is a medical research descriptive study that tracks patients with a known exposure given similar treatment or examines their medical records for exposure and outcome.
For example, the effects seen may be wholly or partly due to intervening effects such as the placebo effect, Hawthorne effectRosenthal effecttime effects, practice effects or the natural history effect.
Internal validity of case series studies is usually very low, due to the lack of a comparator group exposed to the same array of intervening variables.
Hence only the presence of a comparator group, which is not a feature of case-series studies, will allow a valid estimate of the true treatment effect. Calculating the difference in effects between two treatment groups assumed to be exposed to a very similar array of such intervening effects allows the effects of these intervening variables to cancel out.
Glossary Of Clinical Research - C Jump to navigation Jump to search A case series also known as a clinical series is a type of medical research study that tracks subjects with a known exposure, such as patients who have received a similar treatment,  or examines their medical records for exposure and outcome.
Case report A detailed report of the diagnosis, treatment, and follow-up of an individual patient Case reports also contain some demographic information about the patient for example, age, gender, ethnic origin Case series may be confounded by selection bias, which limits statements on the causality of correlations observed; for example, physicians who look at patients with a certain illness and a suspected linked exposure will have a selection bias in that they have drawn their patients from a narrow selection namely their hospital or clinic.
It can be retrospective or prospective and usually involves a smaller number of patients than more powerful case-control studies or randomized controlled trials. Case series may be consecutive  or non-consecutive,  depending on whether all cases presenting to the reporting authors over a period were included, or only a selection.
NCI Case report form A printed, optical, or electronic document designed to record all of the protocol-required information to be reported to the Case series may be consecutive or non-consecutive, depending on whether all cases presenting to the reporting authors over a period were included, or only a selection.
Case series have a descriptive study design ; unlike studies that employ an analytic design e.2. Case study and case series 1.
KNOWLEDGE FOR THE BENEFIT OF HUMANITYKNOWLEDGE FOR THE BENEFIT OF HUMANITY PUBLIC HEALTH AND EPIDEMIOLOGY (HFS) Epidemiological Study Designs: CASE STUDY, CASE SERIES mi-centre.com MohdMohd RazifRazif ShahrilShahril School of Nutrition &.
Clinical case-series are of value in epidemiology for: Studying symptoms and signs Creating case definitions Clinical education, audit and research Case series: Population based When a clinical case-series is complete for a defined geographical area for which the population is known, it is, effectively, a population based case-series consisting.
Case reports and case series in epidemiology and medicine are a type of descriptive study based on singular or grouped uncontrolled observations of patients. Case-series is a descriptive study design and as the name suggests, its just a series of cases of any particular disease or disease discrepancy that one might observe in one's clinical practice etc.
Clarifying the distinction between case series and cohort studies (the solution) In the following report, we propose a conceptualization for cohort studies and case series (e.g., sampling) for systematic reviews, including comparative non-randomized studies.
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